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Physico-Chemical and Structural Characterization Capabilities
- Nuclear Magnetic Resonance Spectroscopy (NMR)
- 1H and multinuclear solution-state 1D and 2D NMR from 400 to 950 MHz for carbohydrate structure characterization and purity analysis in isolated samples as well as complex biomatrices.
- Multinuclear solid-state NMR
- Gas Chromatography/Mass Spectrometry (GC/MS) based upon either of the following techniques:
- Permethylated alditol chemistry for linkage analysis, monomer type analysis and monomer substitution.
- Enzymatic degradation for analysis of primary and secondary sidechain linkages, length and compositions of sidechains and branch points.
- Electrospray Mass Spectrometry (ES-MS)
- Matrix Assisted Laser Desorption Ionization - Time-of-Flight Mass Spectrometry (MALDI-TOF-MS)
- Multi-detector Gel Permeation Chromatography (GPC) using Multi-Angle Laser Light Scattering (MALLS), Differential Viscometry (DV) and Refractive Index (RI) detection systems
- Surface Plasmon Resonance Spectroscopy (SPR) for carbohydrate ligand-receptor binding studies
- Size Exclusion Chromatography (SEC) to narrow the molecular weight range, or ranges, of isolated carbohydrates obtained from a complex matrix
- Atomic Force Microscopy (AFM)
- Scanning Electron Microscopy (SEM)
- Optical Spectroscopy including IR, Raman, NIR and UV/Vis
- Optical Microscopy including IR and Raman
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